Education
- Bachelor of Science, Trinity University, 2008
- Doctor of Philosophy, The Scripps Research Institute, 2012
Biography
Research Interests: antibiotic resistance, stress-responsive signaling, chaperone-client protein-protein interactions
Teaching Interests: biochemistry, bioorganic chemistry, and general chemistry
Research in the Ryno lab utilizes techniques in molecular biology, microbiology, and biochemistry and will focus on exploring new methods to mitigate antibiotic resistance. A considerable amount of effort is being placed in the development and discovery of antibiotics that not only inhibit general bacterial viability but also target particular mechanisms of virulence such as toxin function, delivery and adhesion of bacteria. Despite the numerous advances in antibiotic development, the rapid evolution of bacterial resistance to different mechanisms of antibiotic treatment calls for a constant influx of bactericidal agents that work through novel mechanisms.
The Ryno lab will study the problem of antibiotic resistance from two separate angles. We will explore small molecule inhibitors of specific chaperones involved in the protein homeostasis of the periplasm, and we will also investigate specific pathways in Gram-negative bacteria that are involved in stress-responsive signaling and their impact on the formation of biofilm.
ARTICLES
Oberlin News: The Research You Cannot Resist