The Department of Chemistry and Biochemistry hosts guest speaker Lynette Cegelski, Professor of Chemistry at Stanford University. Her presentation will be on the topic of "Discovery and New Chemistry at the Bacterial Cell Surface."
The seminar will be preceded by a light reception at 4:30pm in the David Love Lounge.
Sponsored by the Luke E. Steiner Lecture Fund.
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Abstract
The bacterial cell wall is essential to cell survival and is a major target of antibiotics. Beyond the cell surface, bacteria assemble remarkable architectures to enmesh cells and form biofilm communities implicated in difficult-to-treat infections. Our research is inspired by the challenge and importance of elucidating chemical structure and function in these complex systems. We strive to transform our discoveries into therapeutic strategies and are introducing new antibacterial and anti-virulence compounds and revealing new chemical structures never before observed in nature. I will discuss our approach and discoveries uncovering the underlying chemistry and biological functions of cell walls and biofilms.