Lucas Mcdonald portrait
  • Visiting Assistant Professor of Chemistry


  • BS, The University of Akron, 2011
  • PhD, The University of Akron, 2018

Synthetic organic chemistry, photophysical chemistry, optical imaging in visible and near infrared region, and molecular probes/dyes.

Fall 2018
  • CHEM 101: Structure and Reactivity in Chemistry (laboratory sections)
Spring 2019
  • CHEM 102: Principles of Chemistry (laboratory sections)

  • Wright, Brian D.; Shah, Parth N.; McDonald, L. J.; Shaeffer, Michael L.; Wagers, Patrick O.; Panzner, Matthew J.; Smolen, Justin; Tagaev, Jasur; Tessier, Claire A.; Cannon, Carolyn L.; Youngs, Wiley J. “Synthesis, characterization, and antimicrobial activity of silver carbene complexes derived from 4,5,6,7-tetrachlorobenzimidazole against antibiotic resistant bacteria.” Dalton Trans., 2012, 41, 6500.
  • Wright, B. D.; Deblock, M. C.; Wagers, P. O.; Duah, E.; Robishaw, N. K.; Shelton, K. L.; Southerland, M. R.; Debord, M. A.; Kersten, K. M.; McDonald, L. J.; Stiel, J. A.; Panzner, M. J.; Tessier, C. A.; Paruchuri, S.; Youngs, W. J. “Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines.” Med. Chem. Res. 2015, 24 (7), 2838–2861.
  • Liu, B.; Pang, Y.; Bouhenni, R.; Duah, E.; Paruchuri, S.; McDonald, L. “A step toward simplified detection of serum albumin on SDS-PAGE using an environment-sensitive flavone sensor.” Chem. Commun. 2015, 51 (55), 11060–11063.
  • Boonkitpatarakul, K.; Wang, J.; Niamnont, N.; Liu, B.; Mcdonald, L.; Pang, Y.; Sukwattanasinitt, M. “Novel Turn-On Fluorescent Sensors with Mega Stikes’ Shifts for Dual Detection of Al3+ and Zn2+.” ACS Sensors 2016, 1 (2), 144–150.
  • McDonald, L.; Wang, J.; Alexander, N.; Li, H.; Liu, T.; Pang, Y. “Origin of Water-Induced Fluorescence Turn-On from a Schiff Base Compound: AIE or H-Bonding Promoted ESIPT?” J. Phys. Chem. B 2016, 120 (4), 766–772.
  • Liu, B.; Bi, X.; McDonald, L.; Pang, Y.; Liu, D.; Pan, C.; Wang, L. “Solvatochromatic fluorescent probes for recognition of human serum albumin in aqueous solution: Insights into structure-property relationship.” Sensors Actuators, B Chem. 2016, 236, 668–674.
  • Liu, B.; McDonald, L.; Liu, Q.; Bi, X.; Zheng, J.; Wang, L.; Pang, Y. “A flavoniod-based light-up bioprobe with intramolecular charge transfer characteristics for wash-free fluorescence imaging in vivo.” Sensors Actuators, B Chem. 2016, 235, 309–315.
  • McDonald, L.; Liu, B.; Taraboletti, A.; Whiddon, K.; Shriver, L. P.; Konopka, M.; Liu, Q.; Pang, Y. “Fluorescent flavonoids for endoplasmic reticulum cell imaging.” J. Mater. Chem. B 2016, 4 (48), 7902–7908.
  • Dahal, D.; McDonald, L.; Bi, X.; Abeywickerama, C.; Gombedza, F.; Paruchuri, S.; Konopka, M.; Pang, Y. “An NIR-Emittinng Lysosome-Targeting Probe with Large Stokes’ Shift via Coupling Cyanine and Excited-State Intramolecular Proton Transfer.” Chem. Comm. 2017, DOI: 10.1039/c7cc00700k.
  • Bi, X.; Liu, B.; McDonald, L.; Pang, Yi.  “Excited-State Intramolecular Proton Transfer (ESIPT) Flavonoid Dyes: A Close Look by Low Temperature.”  J. Phys. Chem. B 2017, 121, 4981-4986.
  • Bertman, K.; Abeywickrama, C.; Baumann, H.; Alexander, N.; McDonald, L. Konopka, M.; Shriver, L.; Pang, Y.  “A fluorescent flavonoid for lysosome detection in live cells under “wash free” conditions.”  J. Phys. Chem. B 2018

  • 2017-2018 The Dr. Henry and Jean Stevens Graduate Fellowship in Chemistry.
  • 2016-2017 The Dr. Franklin Strain Graduate Scholarship in Chemistry, The University of Akron.
  • 2015 Outstanding Teaching Assistant Award, The University of Akron.
  • 2010-2011 Analytic Chemist Award, The University of Akron.
  • 2009-2010 Outstanding Chemistry Student of the Year for the ACS, The University of Akron Division.
  • 2008-2009 Outstanding Chemistry Student of the Year for the ACS, Lakeland Community College Division.
  • 2008-2009 Outstanding Chemistry Student of the Year for Lakeland Community College