much appreciated David Young's fine Memorial Minute for
Andrew Bongiorno. But we want to offer a very important
addition to the recitation of his scholarly accomplishments.
Andrew Bongiorno was the co- translator of one of the more
important, monumental works in 20th-century social science--Vilfredo
Pareto's Trattato di Sociologia Generale (in English--The
Mind and Society), 1935, in four volumes.
member, Oberlin Department of Sociology
Vistas and High Plateaus
the Memorial Minute on Andrew Bongiorno through tears. He
often sounded the theme that liberal education develops
the person, not the work that an individual will do. By
way of illustration, a farmer is a person who farms, a doctor
a person who heals. But all good rules admit exceptions.
Andrew was a a teacher, the very embodiment of the idea
of a teacher. His undramatic, unfailing, utter devotion
to teaching was unique in my 50 years of experience in universities.
More than 60 years after freshman English and a sophomore
lit course, I remember salient messages from his teaching.
As with all great art, his teaching appeared effortless.
focused so completely on teaching that he struck many of
us as ascetic, to the point that he surprised me when, during
a visit to his home, he offered cookies. Oberlin opened
new vistas. Andrew Bongiornio showed us high plateaus.
a molecular biologist who has worked with DNA for my whole career,
the cover of the Winter 1999 issue caught my attention. I hate
to be pedantic, but the drawing of DNA has a significant error.
The Watson-Crick double helix should be a right-handed helix,
but what is drawn is left-handed (as is the one on page 16).
Interestingly, your illustrator can draw DNA both ways, because
he got it right on page 14.
of Biochemistry and Cell Biology,
University of New York
I am writing
to correct several errors of fact in Peter Gwynne's DNA article
in the winter issue. These relate specifically to the description
of my research on page 17.
gene we study encodes plasminogen activator inhibitor (PAI-1),
not plasminogen. Plasminogen is not the "substance that degrades
certain blood clots," but rather is converted by plasminogen
activators to plasmin, which degrades blood clots and other
proteins. PAI-1 regulates the conversion of plasminogen to
growth factor TGF beta is not used to treat fibrotic disease.
In fact, it is likely to be the culprit in the fibrosis
and scarring that occurs in chronic inflammatory diseases.
are used to treat these diseases, and they counteract the
effects of TGF beta. Our research is not aimed at "persuading
the two compounds to work effectively in concert," but rather
to understand the molecular mechanisms by which glucocorticoids
antagonize TGF beta. This knowledge could lead to the design
of more selective synthetic glucocorticoids with fewer unwanted
Department of Human Genetics,
University of Michigan Medical School